Grants for small businesses

Grants from companies, foundations and states that small businesses can apply for, plus every federal grant that lists small businesses as eligible.

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Business grants from companies, foundations and states

Kentucky SBIR/STTR Matching Funds Program

Kentucky Cabinet for Economic Development — KY Innovation Up to $150K Small businesses eligible

Closes in 2 days
TechCred

Ohio Department of Development Up to $30K Small businesses eligible

Closes in 6 days
Galaxy Grant

Galaxy of Stars / Hidden Star (501(c)(3) nonprofit) Up to $2,500 Small businesses eligible

Closes in 7 days
Wisconsin International Market Access Grant

Wisconsin Economic Development Corporation Up to $30K Small businesses eligible

Closes in 7 days
Sephora Beauty Grant

Sephora and the Fifteen Percent Pledge Up to $100K Small businesses eligible

Closes in 13 days
Utah Rural Employment Development Incentive

Utah Governor's Office of Economic Development Up to $250K Small businesses eligible

Expected around Nov 15
Tory Burch Foundation Fellows Program

Tory Burch Foundation Up to $2,000 Small businesses eligible

Closes in 24 days
New Jersey UPSKILL Incumbent Worker Training Grants

New Jersey Department of Labor and Workforce Development Up to $250K Small businesses eligible

Expected around Jan 8, 2027
Small Business Advantage Grant

Pennsylvania Department of Environmental Protection Up to $12K Small businesses eligible

Closes Mar 19, 2027
Halstead Grant

Halstead Bead, Inc. $1,000 to $7,500 Small businesses eligible

Closes May 1, 2027
Illinois SBIR/STTR Match Program

Illinois Department of Commerce and Economic Opportunity Up to $250K Small businesses eligible

Closes Jun 30, 2027
Kansas Global Business Expansion Program (K-GLOBE)

Kansas Department of Commerce Up to $10K Small businesses eligible

Closes Jun 30, 2027
One North Carolina Small Business Program (SBIR/STTR Incentive and Matching Funds)

North Carolina Department of Commerce, Office of Science, Technology & Innovation Small businesses eligible

Closes Jun 30, 2027
Connecticut STEP Export General Assistance Fund

Connecticut Department of Economic and Community Development $500 to $10K Small businesses eligible

Closes Jul 1, 2027
Michigan State Trade Expansion Program (MI-STEP)

Michigan Economic Development Corporation (with U.S. SBA STEP funding) Up to $15K Small businesses eligible

Closes Sep 15, 2027
Global NY State Trade Expansion Program (STEP)

Empire State Development (with U.S. SBA STEP funding) $2,000 to $10K Small businesses eligible

Closes Sep 29, 2027
N.C. Passport to Export STEP Program

Economic Development Partnership of North Carolina (with U.S. SBA STEP funding) Up to $12K Small businesses eligible

Closes Sep 29, 2027
Alabama State Trade Expansion Program

Alabama Department of Commerce Small businesses eligible

Rolling or no fixed deadline
Arkansas SBIR Matching Grant

Arkansas Economic Development Commission Up to $100K Small businesses eligible

Rolling or no fixed deadline
Employment Training Panel Small Business Program

California Employment Training Panel Small businesses eligible

Rolling or no fixed deadline
Entreprenista Evolve Grant

Entreprenista Up to $5,000 Small businesses eligible

Rolling or no fixed deadline
Georgia Export Grant (Go Global Georgia)

Georgia Department of Economic Development (with U.S. SBA STEP funding) Small businesses eligible

Rolling or no fixed deadline
Global Access Program (GAP)

Pennsylvania Department of Community & Economic Development (BusinessPA, with U.S. SBA STEP funding) Up to $10K Small businesses eligible

Rolling or no fixed deadline
Going PRO Talent Fund

Michigan Department of Labor and Economic Opportunity Small businesses eligible

Expected, date not set
Hawaii HiSTEP Company Assistance

Hawaii Department of Business, Economic Development and Tourism Up to $15K Small businesses eligible

Expected, date not set
Idaho STEP Financial Assistance Awards

Idaho Department of Commerce $5,000 to $15K Small businesses eligible

Rolling or no fixed deadline
Illinois Grocery Initiative Equipment Upgrade Program (Round 3)

Illinois Department of Commerce and Economic Opportunity $25K to $250K Small businesses eligible

Rolling or no fixed deadline
Incumbent Worker Training (IWT) Grant

CareerSource Florida Up to $100K Small businesses eligible

Rolling or no fixed deadline
Indiana Power Up Employer Training Grant

Indiana Department of Workforce Development Up to $50K Small businesses eligible

Rolling or no fixed deadline
Iowa Export Trade Assistance Program

Iowa Economic Development and Finance Authority Up to $8,000 Small businesses eligible

Rolling or no fixed deadline
Kitty Fund Mompreneur Business Grant

Founders First CDC From $1,000 Small businesses eligible

Expected, date not set
Louisiana STEP Grants

Louisiana Economic Development Up to $10K Small businesses eligible

Rolling or no fixed deadline
Maine STEP Financial Assistance Awards

Maine International Trade Center $3,000 to $8,000 Small businesses eligible

Expected, date not set
Maryland ExportMD Program

Maryland Department of Commerce Up to $5,000 Small businesses eligible

Rolling or no fixed deadline
Massachusetts Workforce Training Fund Express Program

Commonwealth Corporation Up to $15K Small businesses eligible

Rolling or no fixed deadline
Minnesota State Trade and Export Promotion Grant

Minnesota Department of Employment and Economic Development Up to $7,500 Small businesses eligible

Rolling or no fixed deadline
Mississippi On-the-Job Training Reimbursements

Mississippi Department of Employment Security Small businesses eligible

Rolling or no fixed deadline
Missouri State Trade Expansion Program

Missouri Department of Economic Development Small businesses eligible

Rolling or no fixed deadline
Montana Incumbent Worker Training

Montana Department of Labor and Industry Small businesses eligible

Rolling or no fixed deadline
NC IDEA SEED Grant

NC IDEA Up to $50K Small businesses eligible

Expected, date not set
Nebraska State Trade Expansion Program

Nebraska Department of Economic Development Small businesses eligible

Rolling or no fixed deadline
Nevada Silver State Works On-the-Job Training

Nevada Department of Employment, Training and Rehabilitation Small businesses eligible

Rolling or no fixed deadline
New Mexico State Trade Expansion Program

New Mexico Economic Development Department Small businesses eligible

Rolling or no fixed deadline
Oklahoma STEP Fund

Oklahoma Department of Commerce Up to $29K Small businesses eligible

Rolling or no fixed deadline
Oregon Export Promotion Program

Business Oregon Up to $7,500 Small businesses eligible

Rolling or no fixed deadline
Quick Response Training (QRT) Grant

CareerSource Florida Small businesses eligible

Rolling or no fixed deadline
Santander Cultivate Small Business

Santander Bank (with ICIC and Babson College) $2,500 to $20K Small businesses eligible

Expected, date not set
Skill Advance Colorado Training Grants

Colorado Community College System and Colorado Office of Economic Development and International Trade Small businesses eligible

Expected, date not set
Skills Development Fund

Texas Workforce Commission Up to $500K Small businesses eligible

Rolling or no fixed deadline
Skills for Small Business

Texas Workforce Commission $1,000 to $2,000 Small businesses eligible

Rolling or no fixed deadline
South Carolina State Trade Expansion Program

South Carolina Department of Commerce Small businesses eligible

Rolling or no fixed deadline
South Dakota Incumbent Worker Training

South Dakota Department of Labor and Regulation Up to $20K Small businesses eligible

Rolling or no fixed deadline
Tennessee Incumbent Worker Training Grants

Tennessee Department of Labor and Workforce Development Up to $25K Small businesses eligible

Rolling or no fixed deadline
Verizon Small Business Digital Ready $10,000 Grant

Verizon (administered by LISC) Up to $10K Small businesses eligible

Rolling or no fixed deadline
Virginia Jobs Investment Program — Small Business New Jobs

Virginia Economic Development Partnership Small businesses eligible

Rolling or no fixed deadline
Washington STEP Export Vouchers

Washington State Department of Commerce Up to $10K Small businesses eligible

Rolling or no fixed deadline
WEDnetPA Training Funds

WEDnetPA (with Pennsylvania DCED) Up to $50K Small businesses eligible

Rolling or no fixed deadline
West Virginia STEP Export Reimbursements

West Virginia Division of Economic Development Up to $15K Small businesses eligible

Rolling or no fixed deadline
Wyoming State Trade Expansion Program

Wyoming Business Council Up to $5,000 Small businesses eligible

Rolling or no fixed deadline

Due in October 2026

FY2026 Implementation of the Quagga and Zebra Mussel Action Plan (QZAP) in the Western United States

Department of the Interior $50K to $600K Small businesses eligible

Closes today
Long-term health outcomes of people living with spina bifida

Department of Health and Human Services $100K to $300K Small businesses eligible

Closes in 2 days
NASA Innovative Advanced Concepts (NIAC) Phase I

National Aeronautics and Space Administration Up to $225K Small businesses eligible

Closes in 4 days
OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance

Department of Justice Up to $1.2M Small businesses eligible

Closes in 5 days
OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) Technological Investigative Capacity

Department of Justice Up to $675K Small businesses eligible

Closes in 5 days
BJA FY 2026 National Center for Veterans Justice

Department of Justice Up to $4M Small businesses eligible

Closes in 6 days
GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

Department of Health and Human Services Up to $1.3M Small businesses eligible

Closes in 6 days
GREGoRi Innovation Projects (U01 Clinical Trial Optional)

Department of Health and Human Services $3 to $500K Small businesses eligible

Closes in 6 days
GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Department of Health and Human Services Up to $2.3M Small businesses eligible

Closes in 6 days
HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 6 days

Due in November 2026

BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA)

Department of Justice Up to $2M Small businesses eligible

Closes in 9 days
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 9 days
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 9 days
OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

Department of Justice Up to $1.2M Small businesses eligible

Closes in 9 days
Geometric Analysis

U.S. National Science Foundation Small businesses eligible

Closes in 10 days
Topology

U.S. National Science Foundation Small businesses eligible

Closes in 10 days
DoW Bone Marrow Failure, Idea Development Award

Department of Defense Small businesses eligible

Closes in 11 days
DoW Bone Marrow Failure, Investigator-Initiated Research Award

Department of Defense Small businesses eligible

Closes in 11 days
DoW Bone Marrow Failure, Resource Development Award

Department of Defense Small businesses eligible

Closes in 11 days
DoW Reconstructive Transplant, Concept Award

Department of Defense Small businesses eligible

Closes in 11 days
DoW Reconstructive Transplant, Investigator-Initiated Research Award

Department of Defense Small businesses eligible

Closes in 11 days
Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed

Department of the Interior $10K to $50K Small businesses eligible

Closes in 11 days
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 12 days
Request for Information - Gauging Investor Interest in the Development and Commercialization of Subsurface Energy Technologies

Department of Energy $1 to $2 Small businesses eligible

Closes in 12 days
DoW Parkinson’s, Early Investigator Research Award

Department of Defense Small businesses eligible

Closes in 13 days
DoW Parkinson’s, Investigator-Initiated Research Award

Department of Defense Small businesses eligible

Closes in 13 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes in 13 days
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $300K Small businesses eligible

Closes in 17 days
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 17 days
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 17 days
Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 17 days
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $150K Small businesses eligible

Closes in 17 days
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 17 days
Pilot Projects to Enhance the Human Virome Program (R03 Clinical Trials Not Allowed)

Department of Health and Human Services $50K to $100K Small businesses eligible

Closes in 17 days
DoW Spinal Cord Injury, Clinical Translation Research Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Spinal Cord Injury, Clinical Trial Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Spinal Cord Injury, Investigator-Initiated Research Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Spinal Cord Injury, Translational Research Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Vision, Clinical Trial Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Vision, Investigator-Initiated Research Award

Department of Defense Small businesses eligible

Closes in 19 days
DoW Vision, Translational Research Award

Department of Defense Small businesses eligible

Closes in 19 days
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

Department of Health and Human Services Up to $1.1M Small businesses eligible

Closes in 20 days
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes in 20 days
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 20 days
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)

Department of Health and Human Services Up to $750K Small businesses eligible

Closes in 20 days
Cooperative Agreement for affiliated Partner with Great Lakes-Northern Forest Cooperative Ecosystem Studies Unit

Department of the Interior $1 to $485K Small businesses eligible

Closes in 21 days
Applied Mathematics

U.S. National Science Foundation Small businesses eligible

Closes in 23 days
Astronomy and Astrophysics Research Grants

U.S. National Science Foundation Small businesses eligible

Closes in 23 days
DoW Joint Warfighter Medical, Military Medical Research and Development Award

Department of Defense Small businesses eligible

Closes in 23 days
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)

Department of Health and Human Services Up to $50K Small businesses eligible

Closes in 23 days
NIJ FY 2026 Crime and Justice Research

Department of Justice Up to $5M Small businesses eligible

Closes in 23 days
NIJ FY 2026 Evaluation of the Effectiveness of the Bureau of Justice Assistance (BJA) Byrne State Crisis Intervention Program (SCIP)

Department of Justice Up to $5.9M Small businesses eligible

Closes in 23 days
NIJ FY 2026 Research and Evaluation on Human Trafficking

Department of Justice Up to $2.5M Small businesses eligible

Closes in 23 days
NIJ FY 2026 Research and Evaluation on Justice System Responses to Illegal Immigration

Department of Justice Up to $3M Small businesses eligible

Closes in 23 days
OJJDP FY 2026 Internet Crimes Against Children On-Line Child Protection System (ICACCOPS)

Department of Justice Up to $900K Small businesses eligible

Closes in 23 days
Plasma Physics

U.S. National Science Foundation Small businesses eligible

Closes in 23 days
Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 24 days
Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 24 days
NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes in 24 days
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes in 24 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes in 24 days
Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)

Department of Health and Human Services Small businesses eligible

Closes in 24 days
DoW Breast Cancer, Breakthrough Award Levels 1 and 2

Department of Defense Small businesses eligible

Closes in 25 days
DoW Breast Cancer, Clinical Research Extension Award

Department of Defense Small businesses eligible

Closes in 25 days
DOW Combat Readiness – Medical Research Program Translational Research Award

Department of Defense Small businesses eligible

Closes in 25 days
DoW Orthopaedic, Applied Research Award

Department of Defense Small businesses eligible

Closes in 25 days
DoW Orthopaedic, Clinical Research Award

Department of Defense Small businesses eligible

Closes in 25 days
DoW Rare Cancers Idea Development Award

Department of Defense Small businesses eligible

Closes in 25 days
DoW Rare Cancers Resource and Community Development Award

Department of Defense Small businesses eligible

Closes in 25 days
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes in 25 days
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes in 25 days
DoW Toxic Exposures Clinical Trial Award

Department of Defense Small businesses eligible

Closes in 26 days
DoW Toxic Exposures Investigator Initiated Research Award

Department of Defense Small businesses eligible

Closes in 26 days
DoW Toxic Exposures Translational Research Award

Department of Defense Small businesses eligible

Closes in 26 days
Easement Restoration and Stewardship

Department of Agriculture $250K to $5M Small businesses eligible

Closes in 26 days
FY27 Small Business Development Center State of Kansas Network Rebid

Small Business Administration $778K to $1.1M Small businesses eligible

Closes in 26 days
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes in 26 days
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 26 days
Unlocking New Levels of Output and Capacity for Key Subsurface Resources (UNLOCK)

Department of Energy $3M to $5M Small businesses eligible

Closes in 27 days
Unlocking New Levels of Output and Capacity for Key Subsurface Resources SBIR/STTR (UNLOCK SBIR/STTR)

Department of Energy $323K to $4.6M Small businesses eligible

Closes in 27 days
Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 30 days
Cellular Senescence Network (SenNet): SenNet Data Coordination and Integration Center (SenNet DCIC) (UM1 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 30 days
Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 30 days
NIJ FY 2026 Research and Evaluation on School Safety

Department of Justice Up to $5M Small businesses eligible

Closes in 30 days
NIJ FY 2026 Research on Gender Dysphoria and Violent Crime

Department of Justice Up to $1M Small businesses eligible

Closes in 30 days
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Nov 24
Advanced Nuclear Energy Licensing Cost-Share Grant Program

Department of Energy $5,000 to $8M Small businesses eligible

Closes Nov 30
NIJ FY 2026 Research and Evaluation on Drones as First Responders

Department of Justice Up to $3.5M Small businesses eligible

Closes Nov 30
NIJ FY 2026 Research and Evaluation on Violent Crime: Gangs and Organized Criminal Groups (Domestic and Transnational)

Department of Justice Up to $3M Small businesses eligible

Closes Nov 30
NIJ FY 2026 Research on the Abuse, Neglect, and Exploitation of Elderly Individuals

Department of Justice Up to $1.8M Small businesses eligible

Closes Nov 30

Due in December 2026

Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT)

Department of Energy $2M to $20M Small businesses eligible

Closes Dec 1
Computational Mathematics

U.S. National Science Foundation $1 to $1.2M Small businesses eligible

Closes Dec 1
John H. Prescott Marine Mammal Rescue Assistance Grant

Department of Commerce $1 to $150K Small businesses eligible

Closes Dec 1
National Center for Construction Safety and Health Research and Translation (U54)

Department of Health and Human Services $3M to $5.8M Small businesses eligible

Closes Dec 1
OVC FY 2026 Specialized Human Trafficking Assistance: Task Forces and Legal Services

Department of Justice Up to $3M Small businesses eligible

Closes Dec 1
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)

Department of Health and Human Services Small businesses eligible

Closes Dec 2
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 4
MPPEP Phase 3 Invasive Wild-Caught Catfish

Department of Agriculture $50K to $2M Small businesses eligible

Closes Dec 7
Silicon Carbide Cladding Lead Test Rod Development-Phase 1

Department of Energy Up to $62.5M Small businesses eligible

Closes Dec 7
Cooperative Research Agreements Related to the World Trade Center Health Program (U01)

Department of Health and Human Services Up to $550K Small businesses eligible

Closes Dec 8
Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

Department of Health and Human Services Up to $365K Small businesses eligible

Closes Dec 8
Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)

Department of Health and Human Services Up to $800K Small businesses eligible

Closes Dec 14
Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $1.5M Small businesses eligible

Closes Dec 14
IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed)

Department of Health and Human Services Up to $4M Small businesses eligible

Closes Dec 14
Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $2M Small businesses eligible

Closes Dec 14
Statistics

U.S. National Science Foundation Small businesses eligible

Closes Dec 15
The Genesis Mission: Transforming Science and Energy with AI

Department of Energy - Office of Science $500K to $16M Small businesses eligible

Closes Dec 17
NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research

Department of Defense Small businesses eligible

Closes Dec 30
F26AS00083 Aquatic Invasive Species Grants to Great Lakes States - Fiscal Year 2026 Great Lakes Restoration Initiative

Department of the Interior $100K to $600K Small businesses eligible

Closes Dec 31
F26AS00084 Aquatic Invasive Species Grants to Great Lakes Tribes - Fiscal Year 2026 Great Lakes Restoration Initiative

Department of the Interior $20K to $100K Small businesses eligible

Closes Dec 31
F26AS00085 Aquatic Invasive Species Interjurisdictional Grants to the Great Lakes States and Tribes - Fiscal Year 2026 Great Lakes Restoration Initiative

Department of the Interior $20K to $924K Small businesses eligible

Closes Dec 31
SEFSC Bluefin Tuna Research Program

Department of Commerce $25K to $300K Small businesses eligible

Closes Dec 31

Due in January 2027

ERDC Broad Agency Announcement

Department of Defense Up to $1000M Small businesses eligible

Closes Jan 1, 2027
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jan 7, 2027
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jan 7, 2027
Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)

Department of Health and Human Services Up to $250K Small businesses eligible

Closes Jan 7, 2027
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 11, 2027
Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)

Department of Health and Human Services Up to $700K Small businesses eligible

Closes Jan 11, 2027
Human Networks and Data Science (HNDS)

U.S. National Science Foundation $10K to $1.2M Small businesses eligible

Closes Jan 14, 2027
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes Jan 15, 2027
Linguistics

U.S. National Science Foundation Small businesses eligible

Closes Jan 15, 2027
NOI: PROSPECT Program: Providing Opportunities for Specialized Education in Critical Technologies

Department of Energy Up to $1 Small businesses eligible

Closes Jan 15, 2027
Social Psychology

U.S. National Science Foundation Small businesses eligible

Closes Jan 15, 2027
Decision, Risk and Management Sciences (DRMS)

U.S. National Science Foundation Small businesses eligible

Closes Jan 19, 2027
Improving Undergraduate STEM Education: Directorate for STEM Education (IUSE: EDU)

U.S. National Science Foundation $200K to $2M Small businesses eligible

Closes Jan 20, 2027
National Bycatch Reduction Engineering Program (BREP) - FY2026/27

Department of Commerce $50K to $400K Small businesses eligible

Closes Jan 22, 2027
Medical Scientist Training Program (MSTP) (T32)

Department of Health and Human Services Small businesses eligible

Closes Jan 25, 2027
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 26, 2027
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 26, 2027
National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 26, 2027
Diabetes Research Centers (P30 Clinical Trial Optional)

Department of Health and Human Services Up to $1M Small businesses eligible

Closes Jan 27, 2027
Specialized Alcohol Research Centers (P50 Clinical trial Optional)

Department of Health and Human Services Up to $1.1M Small businesses eligible

Closes Jan 27, 2027
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $750K Small businesses eligible

Closes Jan 28, 2027
Translational Neural Devices (R61/R33 - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 28, 2027
Immune Tolerance Network (UM1 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 29, 2027
Minor Use Minor Species Development of Drugs (R01)

Department of Health and Human Services Up to $250K Small businesses eligible

Closes Jan 29, 2027
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 29, 2027
Agriculture Innovation Center Grant Program

Department of Agriculture $600K to $1M Small businesses eligible

Closes Jan 31, 2027

Due in February 2027

Cognitive Neuroscience (CogNeuro)

U.S. National Science Foundation Small businesses eligible

Closes Feb 1, 2027
Mathematical Sciences Infrastructure Program

U.S. National Science Foundation Small businesses eligible

Closes Feb 2, 2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

Department of Health and Human Services Up to $1.5M Small businesses eligible

Closes Feb 3, 2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Feb 3, 2027
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Feb 8, 2027
Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Feb 8, 2027
A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)

U.S. National Science Foundation $100K to $250K Small businesses eligible

Closes Feb 9, 2027
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $700K Small businesses eligible

Closes Feb 9, 2027
Science of Learning and Augmented Intelligence (SL)

U.S. National Science Foundation From $550 Small businesses eligible

Closes Feb 10, 2027
Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)

Department of Health and Human Services Up to $750K Small businesses eligible

Closes Feb 10, 2027
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Feb 11, 2027
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $700K Small businesses eligible

Closes Feb 11, 2027
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Feb 11, 2027
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)

Department of Health and Human Services $500K to $775K Small businesses eligible

Closes Feb 11, 2027
Advancing Global Health

Department of State $500K to $250M Small businesses eligible

Closes Feb 14, 2027
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Feb 26, 2027

Due in March 2027

Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Mar 1, 2027
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Mar 4, 2027
Coordinating Center for National Resource Network for the Study of Human Auditory and Vestibular Disorders (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes Mar 5, 2027
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Mar 5, 2027
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

Department of Health and Human Services Up to $1.5M Small businesses eligible

Closes Mar 5, 2027
High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Mar 6, 2027
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Mar 6, 2027
Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Mar 6, 2027
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Mar 10, 2027
Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Mar 16, 2027
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Mar 16, 2027
Deployed Warfighter Protection FY27

Department of Defense $20K to $1.1M Small businesses eligible

Closes Mar 17, 2027

Due in April 2027

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes Apr 9, 2027
Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $250K Small businesses eligible

Closes Apr 15, 2027
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 18, 2027
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 20, 2027
Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks

Department of Energy Small businesses eligible

Closes Apr 26, 2027
NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 28, 2027
NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 28, 2027
F26AS00105 National Fish Passage Program

Department of the Interior $1 to $1M Small businesses eligible

Closes Apr 30, 2027
LPS Qubit Collaboratory (LQC)

Department of Defense Small businesses eligible

Closes Apr 30, 2027

Due in May 2027

Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes May 25, 2027
NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Up to $400K Small businesses eligible

Closes May 26, 2027
NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes May 26, 2027
Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $3.5M Small businesses eligible

Closes May 28, 2027
U.S.-Africa Strategic Investment Program

Department of State $5M to $50M Small businesses eligible

Closes May 31, 2027

Due in June 2027

Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 2, 2027
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 2, 2027
NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jun 14, 2027
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 15, 2027
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jun 15, 2027
Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 17, 2027

Due in July 2027

Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jul 2, 2027
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2027
NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2027
NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2027
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 17, 2027

Due in August 2027

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Department of Health and Human Services Up to $150K Small businesses eligible

Closes Aug 11, 2027
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Aug 18, 2027

Due in September 2027

Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 10, 2027
Department of Defense HIV/AIDS Prevention Program

Department of Defense Small businesses eligible

Closes Sep 18, 2027
Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences

U.S. National Science Foundation $1 to $1.2M Small businesses eligible

Closes Sep 20, 2027
NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 25, 2027
Clinical and Translational Science Award (UM1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Sep 28, 2027
Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $250K Small businesses eligible

Closes Sep 29, 2027
CHEERS Open Period 1 - All Technical Areas

Department of Defense Small businesses eligible

Closes Sep 30, 2027
CHEERS Open Period 2 - All Technical Areas

Department of Defense Small businesses eligible

Closes Sep 30, 2027
DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research

Department of Defense Small businesses eligible

Closes Sep 30, 2027
FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

Department of Energy - Office of Science $5,000 to $10M Small businesses eligible

Closes Sep 30, 2027

Due in October 2027

Home Study and Post-Release Services for Unaccompanied Alien Children

Department of Health and Human Services $1M to $100M Small businesses eligible

Closes Oct 1, 2027
BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 4, 2027
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 8, 2027
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 8, 2027
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Oct 12, 2027
NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 14, 2027
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 14, 2027
Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027

Search all 455 open grants

Rolling or no fixed deadline

Accountable Institutions and Behavior (AIB)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Chemical Process Systems (CPS)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Computational and Data-Enabled Science and Engineering

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Continuing Human Enabling Enhancing Restoring and Sustaining

Department of Defense Small businesses eligible

Rolling or no fixed deadline
Crosscutting Activities in Materials Research

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Cyberinfrastructure for Public Access and Open Science

U.S. National Science Foundation $50K to $600K Small businesses eligible

Rolling or no fixed deadline
Economics

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Engineering (ENG): Chemical, Bioengineering, Energy, and Transport Systems (CBET)

U.S. National Science Foundation From $500K Small businesses eligible

Rolling or no fixed deadline
Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Engineering (ENG): Electrical, Communications, and Computing Systems (ECCS)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Engineering Biological and Biomedical Systems (EBBS)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
EONS 2018: Appendix E Minority University Research and Education Project (MUREP) for Sustainability and Innovation Collaborative – (MUSIC)

National Aeronautics and Space Administration Up to $450K Small businesses eligible

Rolling or no fixed deadline
Foundational Research in Robotics

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Fundamental Research to Counter Weapons of Mass Destruction

Department of Defense Small businesses eligible

Rolling or no fixed deadline
Geosciences Core Research: Atmospheric, Geospace, Earth and Ocean Sciences (GEO Core)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Growing Research Access for Nationally Transformative Economic Development (GRANTED)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
High-Risk Research in Biological Anthropology and Archaeology (HRRBAA)

U.S. National Science Foundation Up to $35K Small businesses eligible

Rolling or no fixed deadline
Law & Science (LS)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Long Range Broad Agency Announcement (BAA) for NSWC Crane

Department of Defense Small businesses eligible

Rolling or no fixed deadline
MPS Astronomical Sciences Research Programs (MPS Astro)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
MPS Physics Research Programs (MPS Physics)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Multilateral Partnerships Leveraging Excellence

U.S. National Science Foundation From $200K Small businesses eligible

Rolling or no fixed deadline
NASA Innovative Advanced Concepts (NIAC) Phase II

National Aeronautics and Space Administration Small businesses eligible

Rolling or no fixed deadline
National Facilities

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Ocean Drilling Program

U.S. National Science Foundation From $300K Small businesses eligible

Rolling or no fixed deadline
Pioneering Aerospace Capabilities, Engineering and Research (PACER)

Department of Defense Small businesses eligible

Rolling or no fixed deadline
Professional Formation of Engineers (PFE)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Renewable Energy Systems and Energy Efficiency Improvements Program

Department of Agriculture $1,500 to $500K Small businesses eligible

Rolling or no fixed deadline
Research in the Formation of Engineers

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Research Infrastructure in the Social and Behavioral Sciences

U.S. National Science Foundation $400K to $2M Small businesses eligible

Rolling or no fixed deadline
Research Interests of the United States Air Force Academy (formerly USAFA-BAA-2021)

Department of Defense Up to $99M Small businesses eligible

Rolling or no fixed deadline
RFI - DOE Infrastructure Work Scope Development

Department of Energy Small businesses eligible

Rolling or no fixed deadline
RFI - DOE R

Department of Energy Small businesses eligible

Rolling or no fixed deadline
Science of Organizations (SoO)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Science of Science: Discovery, Communication and Impact (SoS:DCI)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Security and Preparedness (SAP)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Sociology

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
The Research on Research Security Program (RoRS)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline
Transport Phenomena (TP)

U.S. National Science Foundation Small businesses eligible

Rolling or no fixed deadline

Coming up

Forecast by the funder but not open yet. Dates are estimates.

HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 30
The NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS)

Department of Health and Human Services Small businesses eligible

Expected around Nov 1
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC)

Department of Health and Human Services Small businesses eligible

Expected around Nov 1
The NIDDK Disorders of Gastrointestinal Interoception Consortium Clinical Centers (DGIC)

Department of Health and Human Services Small businesses eligible

Expected around Nov 1
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center

Department of Health and Human Services Small businesses eligible

Expected around Nov 1
The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genomic Research Centers

Department of Health and Human Services Small businesses eligible

Expected around Nov 1
Autism Centers of Excellence P50

Department of Health and Human Services Small businesses eligible

Expected around Nov 2
Autism Centers of Excellence R01

Department of Health and Human Services Small businesses eligible

Expected around Nov 2
Continuation and Expansion of the National Mesothelioma Virtual Bank for Translational Research (U24)

Department of Health and Human Services $750K to $1.1M Small businesses eligible

Expected around Nov 2
NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Nov 2
Functional Target Validation for Alzheimer's Disease-Related Dementias

Department of Health and Human Services Small businesses eligible

Expected around Nov 6
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Expected around Nov 10
Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Nov 10
Precision Approaches in Radiation Synthetic Combinations (PAIRS, RP1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Nov 11
Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)

Department of Health and Human Services Small businesses eligible

Expected around Nov 13
Alliance for Innovation on Maternal Health (AIM) Technical Assistance Center

Department of Health and Human Services Up to $3M Small businesses eligible

Expected around Nov 13
Global Brain and Nervous System Disorders Research Across the Lifespan - Exploratory Grants

Department of Health and Human Services Small businesses eligible

Expected around Nov 15
Teaching Health Center Graduate Medical Education (THCGME) Program

Department of Health and Human Services $160K to $960K Small businesses eligible

Expected around Nov 16
NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Nov 20
CDC National Centers of Excellence in Youth Violence Prevention (YVPCs): Rigorous Evaluation of Prevention Approaches to Prevent and Reduce Youth Violence

Department of Health and Human Services Up to $1.2M Small businesses eligible

Expected around Dec 1
Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Dec 1
Improving Linkage to Care for People with Opioid Use Disorder (U01)

Department of Health and Human Services Up to $550K Small businesses eligible

Expected around Dec 1
Microplastics Research and Resource Coordination Center (U24 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Dec 1
New Investigator Grants to Conduct Research to Prevent Interpersonal Violence and Suicide Among Children and Adolescents (K01)

Department of Health and Human Services Up to $150K Small businesses eligible

Expected around Dec 1
Preventing Suicide and Interpersonal Violence Among Youth and Young Adults

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Dec 1
Research Grants to Rigorously Evaluate Innovative and Promising Approaches to Prevent Firearm-Related Violence and Injuries

Department of Health and Human Services Up to $650K Small businesses eligible

Expected around Dec 1
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0

Department of Health and Human Services Small businesses eligible

Expected around Dec 1
Rigorously Evaluating Approaches to Prevent Child Sexual Abuse and Problematic Sexual Behavior among Youth

Department of Health and Human Services Up to $400K Small businesses eligible

Expected around Dec 1
Residential Services for Unaccompanied Alien Children

Department of Health and Human Services $2M to $5.6M Small businesses eligible

Expected around Dec 8
World Trade Center Health Program Mentored Research Scientist Career Development Award (K01)

Department of Health and Human Services Up to $189K Small businesses eligible

Expected around Dec 8
Field Initiated Projects Program (Development)

Department of Health and Human Services $245K to $250K Small businesses eligible

Expected around Dec 14
Field Initiated Projects Program (Research)

Department of Health and Human Services $245K to $250K Small businesses eligible

Expected around Dec 14
Early Head Start Expansion and Early Head Start - Child Care Partnership Grants in Multiple States

Department of Health and Human Services $1.2M to $5M Small businesses eligible

Expected around Dec 15
Head Start/Early Head Grants in Multiple States

Department of Health and Human Services $1M to $79.7M Small businesses eligible

Expected around Dec 15
Network of the National Library of Medicine Coordinating Center (U24 Clinical Trial Optional)

Department of Health and Human Services Up to $1.5M Small businesses eligible

Expected around Dec 15
Network of the National Library of Medicine Regional Medical Libraries (UG4 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $600K Small businesses eligible

Expected around Dec 15
Network of the National Library of Medicine Training Center (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $750K Small businesses eligible

Expected around Dec 15
Small Business Innovation Research (SBIR) program, Phase I

Department of Health and Human Services $95K to $100K Small businesses eligible

Expected around Dec 16
Family-to-Family Health Information Centers (F2F HIC)

Department of Health and Human Services Up to $97K Small businesses eligible

Expected around Dec 19
Regional Excellence for Access to Comprehensive Care for Hemophilia Networks (REACH Networks)

Department of Health and Human Services Up to $450K Small businesses eligible

Expected around Dec 22
Fiscal Year 2027 Regional Nutrition Hubs

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Dec 29
Centers of Excellence in Healthcare Quality and Safety

Department of Health and Human Services $3.5M to $22M Small businesses eligible

Expected around Jan 4, 2027
Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

Department of Health and Human Services $100K to $500K Small businesses eligible

Expected around Jan 5, 2027
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
NIH Specialized Center Grant (Parent P50)

Department of Health and Human Services Small businesses eligible

Expected around Jan 11, 2027
Residential Services for Unaccompanied Alien Children

Department of Health and Human Services $2M to $5.6M Small businesses eligible

Expected around Jan 12, 2027
Fetal, Infant, and Child Death Review Program

Department of Health and Human Services Up to $5.1M Small businesses eligible

Expected around Jan 20, 2027
Healthy Tomorrows Partnership for Children Program (HTPCP)

Department of Health and Human Services Up to $75K Small businesses eligible

Expected around Jan 20, 2027
HIV/AIDS Clinical Trials Network Clinical Trials Units

Department of Health and Human Services Small businesses eligible

Expected around Jan 22, 2027
HIV/AIDS Clinical Trials Network Laboratory Centers

Department of Health and Human Services Small businesses eligible

Expected around Jan 22, 2027
HIV/AIDS Clinical Trials Network Leadership and Operations Centers

Department of Health and Human Services Small businesses eligible

Expected around Jan 22, 2027
HIV/AIDS Clinical Trials Network Statistical and Data Management Centers

Department of Health and Human Services Small businesses eligible

Expected around Jan 22, 2027
Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases

Department of Health and Human Services Small businesses eligible

Expected around Jan 22, 2027
Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Clinical and Translational Science Award

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Fiscal Year (FY) 2027 State and Regional Primary Care Association (PCA) Cooperative Agreements

Department of Health and Human Services $790K to $4.9M Small businesses eligible

Expected around Jan 25, 2027
Genomic Community Resources (U24 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

Department of Health and Human Services $212K to $2.7M Small businesses eligible

Expected around Jan 25, 2027
National Biomedical Research Centers (P50 Clinical Trial Optional)

Department of Health and Human Services $8M to $11.4M Small businesses eligible

Expected around Jan 25, 2027
National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)

Department of Health and Human Services $961K to $1M Small businesses eligible

Expected around Jan 25, 2027
Single Source: Coordinating Center (CC) for the Small Cell Lung Cancer (SCLC) Consortium (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2027
NIOSH Miner Safety and Health Training Program - Western United States – U60

Department of Health and Human Services Up to $250K Small businesses eligible

Expected around Jan 26, 2027
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System

Department of Health and Human Services Small businesses eligible

Expected around Jan 28, 2027
NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 28, 2027
Health and Extreme Weather Research Coordination and Data Center (U2C - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 29, 2027
Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

Department of Health and Human Services Up to $2M Small businesses eligible

Expected around Jan 29, 2027
NIOSH Mentored Research Scientist Development Award (K01)

Department of Health and Human Services $50K to $100K Small businesses eligible

Expected around Jan 29, 2027
KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 30, 2027
KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jan 30, 2027
RNomics Outreach and Coordination (ROC) Center

Department of Health and Human Services Small businesses eligible

Expected around Feb 1, 2027
RNomics Technology Enhancement Centers

Department of Health and Human Services Up to $2M Small businesses eligible

Expected around Feb 1, 2027
Small Business Innovation Research Program (SBIR) Phase II

Department of Health and Human Services $280K to $288K Small businesses eligible

Expected around Feb 1, 2027
Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding

Department of Health and Human Services Up to $200K Small businesses eligible

Expected around Feb 2, 2027
FY2026/2027 Community Compass Technical Assistance and Capacity Building Program Notice of Funding Opportunity

Department of Housing and Urban Development $250K to $35M Small businesses eligible

Expected around Feb 3, 2027
Occupational Safety and Health Research (R01)

Department of Health and Human Services Up to $680K Small businesses eligible

Expected around Feb 5, 2027
Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional)

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Feb 5, 2027
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Feb 8, 2027
Establishing a Research Network to Guide Foundational Research on Human Consciousness

Department of Health and Human Services Small businesses eligible

Expected around Feb 8, 2027
NIOSH Robotics and Intelligent Mining Technology and Workplace Safety Research (U60)

Department of Health and Human Services Up to $2M Small businesses eligible

Expected around Feb 8, 2027
Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Feb 10, 2027
Digital Health Technology and Reciprocal Innovation to Improve Clinical and Public Health Outcomes

Department of Health and Human Services Small businesses eligible

Expected around Feb 11, 2027
Capacity Building for Global, Regional, and National Immunization Programs

Department of Health and Human Services Up to $120M Small businesses eligible

Expected around Feb 12, 2027
Capacity Building for National Immunization Programs in the Eastern Mediterranean Region

Department of Health and Human Services Small businesses eligible

Expected around Feb 12, 2027
Informing global polio eradication efforts through innovative modeling approaches

Department of Health and Human Services Small businesses eligible

Expected around Feb 12, 2027
RNomics Molecular Standards

Department of Health and Human Services Small businesses eligible

Expected around Feb 15, 2027
Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Feb 15, 2027
Feasibility Studies to Inform the Design of Future Clinical Trials

Department of Health and Human Services Small businesses eligible

Expected around Feb 16, 2027
Innovative Research to Improve Native Hawaiian and Pacific Islander (NHPI) Health Outcomes (R34 - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Feb 16, 2027
Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Expected around Feb 16, 2027
NIOSH Exploratory/Developmental Grant Program (R21)

Department of Health and Human Services Up to $300K Small businesses eligible

Expected around Feb 16, 2027
NIOSH Small Research Grant Program (R03)

Department of Health and Human Services Up to $100K Small businesses eligible

Expected around Feb 16, 2027
Research on the Ethical, Legal and Social Implications (ELSI) of Genomics

Department of Health and Human Services Small businesses eligible

Expected around Feb 16, 2027
The National Network of STI Prevention Training Centers (NNPTC)

Department of Health and Human Services $350K to $1M Small businesses eligible

Expected around Feb 20, 2027
NIH Pragmatic Trials Conducted in Health Care Systems

Department of Health and Human Services Small businesses eligible

Expected around Feb 23, 2027
The Home Visiting Research, Improvement, Sustainability and Evaluation Center (HV-RISE)

Department of Health and Human Services Up to $5M Small businesses eligible

Expected around Feb 23, 2027
World Trade Center Youth Research Coordinating Center (U54)

Department of Health and Human Services Up to $10M Small businesses eligible

Expected around Feb 23, 2027
NIOSH Centers of Excellence for Total Worker Health® (U19)

Department of Health and Human Services $500K to $1.4M Small businesses eligible

Expected around Feb 26, 2027
Bridge2AI Network for AI Health Science

Department of Health and Human Services $1M to $7M Small businesses eligible

Expected around Mar 1, 2027
Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)

Department of Health and Human Services $500K to $750K Small businesses eligible

Expected around Mar 2, 2027
NIOSH Centers for Agriculture, Forestry, and Fishing Safety and Health (U54)

Department of Health and Human Services Up to $2.2M Small businesses eligible

Expected around Mar 3, 2027
NIOSH National Center of Excellence for the Prevention of Childhood Agricultural Injury (U54)

Department of Health and Human Services Up to $1.6M Small businesses eligible

Expected around Mar 3, 2027
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

Department of Health and Human Services $300K to $600K Small businesses eligible

Expected around Mar 4, 2027
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)

Department of Health and Human Services Small businesses eligible

Expected around Mar 4, 2027
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

Department of Health and Human Services Small businesses eligible

Expected around Mar 4, 2027
Core State Injury Prevention Program (Core SIPP)

Department of Health and Human Services Small businesses eligible

Expected around Mar 8, 2027
Promoting Cancer Surveillance Workforce, Education, and Data Use

Department of Health and Human Services Small businesses eligible

Expected around Mar 8, 2027
Rural Communities Opioid Response Program - Overdose Response

Department of Health and Human Services Up to $300K Small businesses eligible

Expected around Mar 10, 2027
Distressed Cities Technical Assistance (DCTA) Program for Fiscal Years 2026 and 2027

Department of Housing and Urban Development $400K to $3M Small businesses eligible

Expected around Mar 11, 2027
Center on Knowledge Translation for Disability and Rehabilitation Research

Department of Health and Human Services $795K to $800K Small businesses eligible

Expected around Mar 15, 2027
Demonstration Projects for Whole-Person Health Models for Women Living with HIV in the South

Department of Health and Human Services Small businesses eligible

Expected around Mar 15, 2027
Rural Health Network Development Program

Department of Health and Human Services $300K to $500K Small businesses eligible

Expected around Mar 16, 2027
Ryan White HIV/AIDS Program Part C Capacity Development Program

Department of Health and Human Services Up to $150K Small businesses eligible

Expected around Mar 16, 2027
Alliance for Innovation on Maternal Health (AIM) Capacity Program

Department of Health and Human Services Up to $230K Small businesses eligible

Expected around Mar 17, 2027
Homeless Veterans’ Reintegration Program (HVRP), Incarcerated Veterans’ Transition Program (IVTP), and the Homeless Women Veterans' and Homeless Veterans' with Children Reintegration Grant Program (HWVHVWC) (referred to collectively as HVRP)

Department of Labor $150K to $500K Small businesses eligible

Expected around Mar 17, 2027
Maternal and Child Health Encounters Networks (MCHEK)

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Mar 18, 2027
Rural Residency Planning and Development Program

Department of Health and Human Services Up to $750K Small businesses eligible

Expected around Mar 18, 2027
Rural Health Value Program

Department of Health and Human Services Up to $650K Small businesses eligible

Expected around Mar 20, 2027
Implementation Research on Multi-component Community-Clinical Linkage Approaches for Diabetes Prevention and Management

Department of Health and Human Services $500K to $725K Small businesses eligible

Expected around Mar 22, 2027
Pilot Testing, Implementation, and Evaluation of the Cervical, Breast and Colorectal Cancer Clinical Decision Support Tools

Department of Health and Human Services Small businesses eligible

Expected around Mar 23, 2027
Rural Communities Opioid Response Program - Child and Adolescent Behavioral Health

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Mar 23, 2027
Rural Communities Opioid Response Program - Evaluation

Department of Health and Human Services Up to $5M Small businesses eligible

Expected around Mar 23, 2027
Rural Health Network Development Planning Program

Department of Health and Human Services Up to $100K Small businesses eligible

Expected around Mar 23, 2027
National Breastfeeding Support, Implementation, and Hospital Quality Improvement Initiative

Department of Health and Human Services Small businesses eligible

Expected around Mar 26, 2027
Rehabilitation Research and Training Center (RRTC): National Research Center for Parents with Disabilities

Department of Health and Human Services $920K to $925K Small businesses eligible

Expected around Mar 26, 2027
Appalachian Region Healthcare Support Program

Department of Health and Human Services Up to $2.5M Small businesses eligible

Expected around Mar 27, 2027
Continuing Enhanced National Surveillance for Prion Diseases in the United States

Department of Health and Human Services $3M to $25M Small businesses eligible

Expected around Mar 27, 2027
Drug-Free Communities (DFC) Support Program – NEW (Year 1)

Department of Health and Human Services Up to $125K Small businesses eligible

Expected around Mar 31, 2027
Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD)

Department of Health and Human Services Small businesses eligible

Expected around Mar 31, 2027
Traumatic Brain Injury Model Systems Centers

Department of Health and Human Services $560K to $640K Small businesses eligible

Expected around Apr 1, 2027
Rural Communities Opioid Response Program - Community Systems Development

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Apr 6, 2027
Supporting Community Application of Life-Saving Evidence to Prevent Injury and Violence (SCALE)

Department of Health and Human Services Small businesses eligible

Expected around Apr 6, 2027
Burn Injury Model System Centers

Department of Health and Human Services $560K to $640K Small businesses eligible

Expected around Apr 8, 2027
NIOSH Support for Conferences and Scientific Meetings (R13 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $20K Small businesses eligible

Expected around Apr 12, 2027
NIOSH Support for Conferences and Scientific Meetings (U13 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $30K Small businesses eligible

Expected around Apr 12, 2027
Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities

Department of Health and Human Services $970K to $975K Small businesses eligible

Expected around Apr 15, 2027
Comprehensive Suicide Prevention Program for States

Department of Health and Human Services $650K to $1.2M Small businesses eligible

Expected around Apr 17, 2027
State Biomonitoring Cooperative Agreement

Department of Health and Human Services $750K to $900K Small businesses eligible

Expected around Apr 19, 2027
Rural Maternity and Obstetrics Management Strategies Program

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Apr 20, 2027
Infant-Toddler Court Program–National Resource Center

Department of Health and Human Services Up to $6.8M Small businesses eligible

Expected around Apr 21, 2027
Infant-Toddler Court Program–State Awards

Department of Health and Human Services Up to $700K Small businesses eligible

Expected around Apr 21, 2027
Rehabilitation Engineering Research Center on Technologies for People Who are Blind or have Low Vision

Department of Health and Human Services $970K to $975K Small businesses eligible

Expected around Apr 22, 2027
Maternal-Child Surveillance and Partnerships for Action, Results, and Knowledge

Department of Health and Human Services Small businesses eligible

Expected around Apr 26, 2027
Chronic Disease Education and Awareness

Department of Health and Human Services Small businesses eligible

Expected around Apr 30, 2027
Promoting Population Health through Increased Capacity in Alcohol Epidemiology & the Prevention of Excessive Alcohol Use

Department of Health and Human Services Small businesses eligible

Expected around Apr 30, 2027
Telehealth Nutrition Services Network Grant Program

Department of Health and Human Services Up to $300K Small businesses eligible

Expected around May 1, 2027
Alzheimer's Disease Programs Initiative (ADPI) - Developing Dementia-Capable Community Health Worker Programs in the National Aging Network

Department of Health and Human Services $200K to $250K Small businesses eligible

Expected around May 3, 2027
Statewide Perinatal Quality Collaboratives: Improving Perinatal Care and Outcomes

Department of Health and Human Services Small businesses eligible

Expected around May 3, 2027
Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around May 8, 2027
Elder Justice Innovation Grants FY2027

Department of Health and Human Services $250K to $500K Small businesses eligible

Expected around May 17, 2027
National Adult Protective Services Training Center

Department of Health and Human Services $1M to $1.3M Small businesses eligible

Expected around May 17, 2027
National Center on Elder Abuse Resource Center

Department of Health and Human Services $856K to $1M Small businesses eligible

Expected around May 17, 2027
DHQP Global NOFO

Department of Health and Human Services Small businesses eligible

Expected around May 20, 2027
Asthma and Allergic Diseases Cooperative Research Centers

Department of Health and Human Services Small businesses eligible

Expected around May 21, 2027
Translational Transplantation Tolerance Cooperative Study Group

Department of Health and Human Services Small businesses eligible

Expected around May 21, 2027
Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use

Department of Health and Human Services Small businesses eligible

Expected around May 24, 2027
A Holistic Approach to Study Non-Addictive Natural Products for Pain Management

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)

Department of Health and Human Services Up to $1.5M Small businesses eligible

Expected around May 25, 2027
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
Coordinating Center for the Claude D. Pepper Older Americans Independence Centers (OAICs)

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed)

Department of Health and Human Services $10K to $80K Small businesses eligible

Expected around May 25, 2027
Partnership with Common Fund Data Ecosystem Resources

Department of Health and Human Services $500K to $1.2M Small businesses eligible

Expected around May 25, 2027
Radiation Exposure Screening and Education Program

Department of Health and Human Services $250K to $500K Small businesses eligible

Expected around May 25, 2027
Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center

Department of Health and Human Services Small businesses eligible

Expected around May 25, 2027
NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

Department of Health and Human Services Up to $375K Small businesses eligible

Expected around May 26, 2027
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers

Department of Health and Human Services Small businesses eligible

Expected around May 27, 2027
Implementation and Evaluation of Databases to Examine AIDS

Department of Health and Human Services Small businesses eligible

Expected around May 27, 2027
Childhood Asthma in Urban Settings Clinical Research Network

Department of Health and Human Services Small businesses eligible

Expected around May 28, 2027
Improved Drug Susceptibility Testing (DST) for Mycobacteria

Department of Health and Human Services Small businesses eligible

Expected around May 28, 2027
Holistic and Evidence-Informed Wellness for STI Prevention

Department of Health and Human Services Small businesses eligible

Expected around May 31, 2027
BRAIN Initiative: Data Archives for the BRAIN Initiative

Department of Health and Human Services Small businesses eligible

Expected around Jun 1, 2027
Clinical Data, Safety and Statistical Centers (CDSSC)

Department of Health and Human Services Small businesses eligible

Expected around Jun 1, 2027
National Viral Hepatitis Education, Awareness, and Capacity Building for Communities and Providers

Department of Health and Human Services Small businesses eligible

Expected around Jun 1, 2027
NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jun 1, 2027
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $300K Small businesses eligible

Expected around Jun 4, 2027
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $150K Small businesses eligible

Expected around Jun 4, 2027
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Jun 8, 2027
BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research

Department of Health and Human Services Small businesses eligible

Expected around Jun 10, 2027
Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

Department of Health and Human Services Up to $600K Small businesses eligible

Expected around Jun 11, 2027
Immune Drivers of Autoimmune Disease

Department of Health and Human Services Small businesses eligible

Expected around Jun 11, 2027
Centers for Research on Neglected Infectious Diseases

Department of Health and Human Services Small businesses eligible

Expected around Jun 15, 2027
INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jun 15, 2027
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development

Department of Health and Human Services Small businesses eligible

Expected around Jun 16, 2027
Limited Competition: BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships

Department of Health and Human Services Small businesses eligible

Expected around Jun 17, 2027
Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jun 18, 2027
Somatic Mosaicism across Human Tissues (SMaHT) Program: Experimental and Computational Technology Development (RM1 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jul 1, 2027
Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jul 1, 2027
Somatic Mosaicism across Human Tissues (SMaHT) Program: National Somatic Mosaicism Commons Data Analysis & Organizational Center (UM1 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jul 1, 2027
Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (R24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Jul 1, 2027
NIAMS Clinical Trial Implementation Cooperative Agreement

Department of Health and Human Services From $250K Small businesses eligible

Expected around Jul 2, 2027
Translational Research in Maternal and Pediatric Pharmacology and Therapeutics

Department of Health and Human Services Small businesses eligible

Expected around Jul 9, 2027
Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Expected around Jul 31, 2027
NIH Director's New Innovator Award (DP2 Clinical Trial Optional)

Department of Health and Human Services Up to $475K Small businesses eligible

Expected around Aug 19, 2027
NIH Director's Transformative Research Award (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Sep 3, 2027
HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Expected around Sep 7, 2027
NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

Department of Health and Human Services Up to $700K Small businesses eligible

Expected around Sep 9, 2027
NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

Department of Health and Human Services Up to $350K Small businesses eligible

Expected around Sep 10, 2027
Claude D. Pepper Older Americans Independence Centers

Department of Health and Human Services Small businesses eligible

Expected around Sep 25, 2027
Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Research Program (U19 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Sep 25, 2027
Small Instruments and Modern Equipment for Shared-use Biomedical Research Facilities and Resources (S15 Clinical Trial Not Allowed)

Department of Health and Human Services $25K to $350K Small businesses eligible

Expected around Sep 27, 2027
Clinical Trials in Organ Transplantation in Children and Adults

Department of Health and Human Services Small businesses eligible

Expected around Sep 30, 2027
Discovery Gateway to Reproductive Health Innovation

Department of Health and Human Services Small businesses eligible

Expected around Oct 1, 2027
Learning Disabilities Research Centers

Department of Health and Human Services Small businesses eligible

Expected around Oct 1, 2027
R3PEATS Grassroots Rigor Projects: Individual Metascience and Individual Laboratory Capacity-Building (RP1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 1, 2027
R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 1, 2027
R3PEATS Rigor Scholar Cohort Awards (K12)

Department of Health and Human Services Small businesses eligible

Expected around Oct 1, 2027
Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC)

Department of Health and Human Services Up to $1M Small businesses eligible

Expected around Oct 1, 2027
Investigator-Focused Award (Parent R35)

Department of Health and Human Services Small businesses eligible

Expected around Oct 4, 2027
Established Clinician Investigator Award to Support Mentoring (KS1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 12, 2027
Mentored Career Transition Award (KT1/R00)

Department of Health and Human Services Small businesses eligible

Expected around Oct 12, 2027
Mentored Clinician Research Scientist Career Development Award (KC1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 12, 2027
Mentored Research Scientist Career Development Award (KR1)

Department of Health and Human Services Small businesses eligible

Expected around Oct 12, 2027
The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes

Department of Health and Human Services Small businesses eligible

Expected around Oct 13, 2027
Partnerships for Advancing Development of Diagnostics for Infectious Diseases

Department of Health and Human Services Small businesses eligible

Expected around Oct 14, 2027
Advancing Screening, Diagnosis, and Referral for Late Talking Children

Department of Health and Human Services Up to $500K Small businesses eligible

Expected around Oct 15, 2027
Intervention Research to Improve Native American Health

Department of Health and Human Services Small businesses eligible

Expected around Oct 18, 2027
LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

Department of Health and Human Services Small businesses eligible

Expected around Oct 18, 2027
Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier

Department of Health and Human Services Small businesses eligible

Expected around Oct 20, 2027
Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource-Constrained Settings--Implementation Science Network (PATC3H-IN)

Department of Health and Human Services Small businesses eligible

Expected around Oct 28, 2027
Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Coordinating Center (CCC) & Data Coordinating Center (DCC)

Department of Health and Human Services Small businesses eligible

Expected around Nov 1, 2027
Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) Infrastructure – Clinical Research Sites (U24 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Nov 1, 2027
Tobacco Centers of Regulatory Science (TCORS) (Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Nov 10, 2027
NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2028
NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)

Department of Health and Human Services Small businesses eligible

Expected around Jan 25, 2028
Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications (U42 Clinical Trial Not Allowed)

Department of Health and Human Services $580K to $900K Small businesses eligible

Expected around Jan 25, 2028
ancient DNA for Modern Genomics (aDMG) Research Projects (U01 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Expected around Feb 1, 2028
Technology Development Program

Department of Health and Human Services Small businesses eligible

Expected around Feb 5, 2028
Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

Department of Health and Human Services $190K to $500K Small businesses eligible

Expected around Feb 16, 2028
NIDCD Research Fellowship for Audiologists

Department of Health and Human Services Small businesses eligible

Expected around May 30, 2028
Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

Department of Health and Human Services Small businesses eligible

Expected, date not set
Center for Research on Complex Generics (U18) Clinical Trials Optional

Department of Health and Human Services Up to $1.5M Small businesses eligible

Expected, date not set
Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required

Department of Health and Human Services $650K to $900K Small businesses eligible

Expected, date not set
Collaborations to Enhance Drug Development and Regulatory Science

Department of Health and Human Services Up to $5M Small businesses eligible

Expected, date not set
Cooperative Agreement for Long Term Data Collection on Antimicrobial Use in Animals (U01) Clinical Trial Not Allowed

Department of Health and Human Services Up to $200K Small businesses eligible

Expected, date not set
Cooperative Agreement to Support a Human Abuse Potential Study of Botanical Kratom (U01 Clinical Trial Required)

Department of Health and Human Services Up to $2M Small businesses eligible

Expected, date not set
Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) Clinical Trials Allowed

Department of Health and Human Services Up to $2M Small businesses eligible

Expected, date not set
Cooperative Agreement to Support Effective Dissemination of Clinical Practice Guidelines

Department of Health and Human Services Up to $1M Small businesses eligible

Expected, date not set
Developing PBPK Model-Based Mechanistic IVIVCs for Long Acting Injectable Suspensions and Implants (U01) Clinical Trial Optional

Department of Health and Human Services Up to $300K Small businesses eligible

Expected, date not set
DIRECTED ENERGY TECHNOLOGY EXPERIMENTATION RESEARCH ADVANCED RESEARCH ANNOUCEMENT (DETER ARA)

Department of Defense Small businesses eligible

Expected, date not set
Educational Funding Opportunity: Expanding education on skin lightening products (U01) Clinical Trials Not Allowed

Department of Health and Human Services Up to $250K Small businesses eligible

Expected, date not set
Evaluating the Cutaneous Pharmacokinetics of Topical Drug Products Using Pharmacokinetic Tomography (U01 Clinical Trial Required)

Department of Health and Human Services Up to $250K Small businesses eligible

Expected, date not set
FDA OMHHE Health Equity Innovation Award: Enhance Equity Funding Opportunity (U01) Clinical Trials Not Allowed

Department of Health and Human Services $250K to $1M Small businesses eligible

Expected, date not set
Health Equity Innovation Award: Enhance Equity Funding Opportunity (U01) Clinical Trials Not Allowed

Department of Health and Human Services Up to $1M Small businesses eligible

Expected, date not set
Identification and Evaluation of Possible Approaches to Addressing Nitrosamine Impurities in Drugs (U01)

Department of Health and Human Services Up to $350K Small businesses eligible

Expected, date not set
Identification of Drug-related and Formulation-Related Factors that Result in Alcohol Dose Dumping of Modified Release Oral Drug Products (U01) Clinical Trial Not Allowed

Department of Health and Human Services Up to $250K Small businesses eligible

Expected, date not set
Improving Predictability of Food-Drug and Drug-Drug Interaction Risks by Utilizing In Vitro Simulated Gastrointestinal Dissolution Model for High-Risk Oral Drug Products (U01) Clinical Trial Optional

Department of Health and Human Services $250K to $500K Small businesses eligible

Expected, date not set
Integrating Machine Learning with Computational Fluid Dynamics Models of Orally Inhaled Drug Products (U01) Clinical Trials Not Allowed

Department of Health and Human Services Small businesses eligible

Expected, date not set
Minor Use Minor Species Development of Drugs (R01)

Department of Health and Human Services Up to $250K Small businesses eligible

Expected, date not set
NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

Department of Health and Human Services Up to $4.5M Small businesses eligible

Expected, date not set
NFRP Outreach and Invitation for Response

Department of Defense Small businesses eligible

Expected, date not set
Novel approaches to support therapeutic development in ultra-rare cancers

Department of Health and Human Services Small businesses eligible

Expected, date not set
OMHHE Educational Funding Opportunity: Expanding education on skin lightening products (U01) Clinical Trials Not Allowed

Department of Health and Human Services Up to $250K Small businesses eligible

Expected, date not set
REACHing Communities (REACH) Consortium (U01) Clinical Trials Optional

Department of Health and Human Services Up to $3M Small businesses eligible

Expected, date not set
Solomon Islands Threshold Program Industry Day

Millennium Challenge Corporation Small businesses eligible

Expected, date not set
Studies Addressing Rare Neurodegenerative Diseases including ALS

Department of Health and Human Services Small businesses eligible

Expected, date not set
Synthesis and Biological Activity Assessment of Different Diastereomers in siRNA Drug LEQVIO (Inclisiran) (U01) Clinical Trial Not Allowed

Department of Health and Human Services Up to $300K Small businesses eligible

Expected, date not set
USDA/USDOI Joint Fire Science Program (JFSP)

Department of the Interior Small businesses eligible

Expected, date not set
Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed

Department of Health and Human Services Up to $300K Small businesses eligible

Expected, date not set

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Questions

How many grants are open for small businesses right now?

544 open grants, 91 closing in the next 30 days, checked daily against official sources.

When is the next deadline?

The next deadline is October 24, 2026 for FY2026 Implementation of the Quagga and Zebra Mussel Action Plan (QZAP) in the Western United States.